Grownup human neural crest-derived stem cells (NCSCs) are present in quite a lot of grownup tissues and present a unprecedented broad developmental potential. Regardless of their nice differentiation capability, growing
Tag: cd3 positive t cells
Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8 + T cell exhaustionCollagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8 + T cell exhaustion
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Tumor extracellular matrix has been associated with drug resistance and immune suppression. Here, proteomic and RNA profiling reveal increased collagen levels in lung tumors resistant to PD-1/PD-L1 blockade. Additionally, elevated