Tag: Fugw Vector

Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer

Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancerGerminal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer

Hypoxia develops in germinal facilities (GCs) induced by mannequin antigens; nevertheless, it’s unknown whether or not tumor-reactive GCs are additionally hypoxic. We recognized GC hypoxia in lymph nodes (LNs) draining