Author: Sophia

SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2

SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2

Dysregulation of protein posttranslational modification (PTM) can result in quite a lot of pathological processes, reminiscent of irregular sperm growth, malignant tumorigenesis, despair, and growing old course of. SIRT7 is

Glucocorticoid-transactivated TSC22D3 attenuates hypoxia- and diabetes-induced Müller glial galectin-1 expression via HIF-1α destabilization.

Galectin-1/LGALS1, a newly acknowledged angiogenic issue, contributes to the pathogenesis of diabetic retinopathy (DR).Galectin-1/LGALS1, a newly acknowledged angiogenic issue, contributes to the pathogenesis of diabetic retinopathy (DR).

Not too long ago, we demonstrated that glucocorticoids suppressed an interleukin-1β-driven inflammatory pathway for galectin-1 expression in vitro and in vivo. Right here, we present glucocorticoid-mediated inhibitory mechanism in opposition