The purpose of this research was to evaluate nailfold capillaroscopic (NC) findings in sufferers with main Sjögren’s syndrome (PSS) with and with out Raynaud’s phenomenon (RP) in addition to within the presence of constructive anti-SSA/Ro and anti-SSB/La antibodies.
Videocapillaroscopy was carried out in 150 sufferers with PSS. Knowledge collected included demographics, presence of RP, PSS signs, antinuclear antibodies, rheumatoid issue, anti-Ro, anti-La, anti-CCP, salivary scintigraphy, labial biopsy, and NC findings. RP was current in 32% of PSS, keratoconjunctivitis sicca in 91%, oral xerosis in 93%, and pores and skin or genital xerosis in 53%.
In sufferers with constructive anti-SSA/Ro (75%) and constructive anti-SSB/La (40%), NC confirmed regular findings in 53% of instances and non-specific in 36%. In sufferers with PSS, NC was regular in 51% of instances and non-specific in 34%. Scleroderma sample was present in 14 sufferers. RP related to PSS had non-specific capillaroscopy in 40% of instances (p = 0.1).
Pericapillary haemorrhages (p = 0.06) and capillary thrombosis (p = 0.2) weren’t elevated, however extra dilated capillaries have been detected in 48% of instances. Sufferers with constructive anti-Ro and/or anti-La haven’t a definite NC profile. Sufferers with RP related to PSS had extra dilated capillaries, however neither pericapillary haemorrhages nor capillary thrombosis was noticed.