Plasmid-mediated gene remedy, being a protected and comparatively cheap therapeutic technique, is stricken by a quick silencing of transgene expression. The silencing severely reduces the long-term effectivity of plasmid vectors. We have now earlier constructed a low-CpG pMBR2 plasmid vector supporting extended expression of transgenes in mesenchymal stem cells in vitro. Lengthy-term expression from the pMBR2 vector was studied for the wild-type mouse secreted alkaline phosphatase gene (mSEAPTwt) and its model devoid of CpGs (mSEAP0) after vector electroporation into mouse hindlimb muscle tissue and hydrodynamic supply to the liver. The mSEAP ranges within the blood have been measured over one yr.
With the pMBR2-mSEAP0 assemble, the mSEAP ranges in leg muscle tissue elevated greater than 2.5-fold within the first two months and remained greater than the preliminary stage till the top of the experiment. Far decrease expression ranges have been noticed with the management pCDNA3.1-mSEAP0 assemble. Expression from pMBR2-mSEAPwt decreased to about 40% after 6 months and remained at related ranges thereafter. Within the mouse liver, expression from pMBR2-mSEAP0 was roughly halved throughout the first 18 weeks after which lower slowly to the ultimate 17% stage.
Expression from pMBR2-mSEAPwt initially dropped to 18% and remained at roughly 10% thereafter. In distinction, expression from pCDNA3.1-mSEAP0 sharply dropped to five% after 2 weeks and remained at almost zero ranges all through the remainder of the experiment. Thus, each vector and transgene ought to have considerably lowered CpG contents to make sure extended plasmid-mediated expression within the liver, whereas minimizing the vector CpG content material is ample for expression in skeletal muscle tissue. The outcomes recommended moreover that the localization of S/MAR parts throughout the transcription unit, in distinction to their exterior location, ends in important discount of the extent of secreted, however not cytoplasmic, proteins.
A delocalizable cationic headgroup along with an oligo-oxyethylene spacer in gemini cationic lipids improves their organic exercise as vectors of plasmid DNA.
Lipoplex nano-aggregates constituted of plasmid DNA (pDNA) pEGFP-C3 and blended cationic liposomes, consisting of a number of percentages of a gemini cationic lipid (GCL) of the 1,2-bis(hexadecyl imidazolium) oxyethylene collection, known as (C16Im)2(C2O)n, with oxyethylene spacers (n = 1, 2 or 3) between the imidazolium cationic teams and the DOPE zwitterionic helper lipid, have been characterised by numerous biophysical and organic approaches carried out at a number of GCL compositions (α), and both the mass or the efficient cost ratio of the lipoplex. The electrochemical research by ζ-potential confirms that the three GCLs yield a 10% decrease efficient cost than the nominal one, whereas compacted pDNA yields solely a 25% efficient destructive cost.
The SAXS research reveals, regardless of the spacer size (n) and efficient cost ratio (ρeff), the presence of two lamellar constructions, i.e., one (Lα,predominant) in the entire GCL composition and one other (Lα,DOPE,wealthy) with greater periodicity values that coexists with the earlier one at low GCL composition (α = 0.2). The cryo-TEM evaluation reveals two kinds of multilamellar constructions consisting of cationic lipidic bilayers with pDNA sandwiched between them: a cluster-type (C-type) at low α = 0.2 and a fingerprint-type (FP-type) at α≥ 0.5, each with related interlamellar spacing (d) in settlement with the Lα,predominant construction decided by SAXS. Transfection efficacies (TEs) of every lipid combination have been decided in 4 totally different cell strains (HEK293T, HeLa, Caco-2 and A549) at a number of α and ρeff values within the absence and presence of serum (FBS).
The optimized formulations (α = 0.2 and ρeff = 2.0) considerably transfect cells a lot better than a business transfection reagent, Lipofectamine 2000 and beforehand studied environment friendly lipoplexes containing different cationic head teams or spacers each within the absence and presence of serum. The exercise of optimized formulations could also be attributed to the mixture of a number of components, equivalent to: (a) the fusogenic character of DOPE which leads to greater fluidity of the lipoplexes at α = 0.2, (b) the coexistence of two lamellar constructions at α = 0.2 that synergizes the TE of those lipid vectors, and primarily (c) the upper biocompatibility of the GCLs reported on this work as a result of presence of two imidazolium cationic teams along with an oligo-oxyethylene spacer.
The size of the spacer within the GCL appears to have much less affect, though (C16Im)2(C2O)n/DOPE-pDNA lipoplexes with n = 1 and three present greater gene transfection than n = 2. All of the optimum formulations reported herein are all extremely environment friendly with negligible ranges of toxicity, and thus, could also be thought of as very promising gene vectors for in vivo purposes
Potentiation of curing by a broad-host-range self-transmissible vector for displacing resistance plasmids to sort out AMR.
Plasmids are potent autos for unfold of antibiotic resistance genes in bacterial populations and sometimes persist within the absence of choice because of environment friendly upkeep mechanisms. We beforehand constructed non-conjugative excessive copy quantity plasmid vectors that effectively displace steady plasmids from enteric micro organism in a laboratory context by blocking their replication and neutralising their dependancy methods. Right here we assess a low copy quantity broad-host-range self-transmissible IncP-1 plasmid as a vector for such curing cassettes to displace IncF and IncK plasmids.
The wild sort plasmid carrying the curing cassette displaces goal plasmids poorly however derivatives with deletions close to the IncP-1 replication origin that elevate copy quantity about two-fold are environment friendly. Verification of this in mini IncP-1 plasmids confirmed that elevated copy quantity was not ample and that the parB gene, korB, that’s central to its partitioning and gene management system, additionally must be included.
Genorise® Universal DNA Mini Kit 100 |
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GR101076-100 | Genorise Scientific | 100 | EUR 357 |
Genorise® Universal DNA Mini Kit 200 |
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GR101077 | Genorise Scientific | 200 | EUR 567 |
Genorise® Universal DNA Mini Kit 500 |
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GR101077-500 | Genorise Scientific | 500 | EUR 1272 |
Methylamp Universal Methylated DNA Kit |
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P-1011 | EpiGentek |
|
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QPCR Kit DNA Universal f Mmix - EACH |
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MOL6608 | Scientific Laboratory Supplies | EACH | EUR 1581.9 |
QPCR Kit DNA Universal m Mmix - EACH |
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MOL6612 | Scientific Laboratory Supplies | EACH | EUR 1581.9 |
VAHTS Universal DNA Library Prep Kit for MGI |
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NDM607-01 | Vazyme | 24 rxn | EUR 879.6 |
VAHTS Universal DNA Library Prep Kit for MGI |
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NDM607-02 | Vazyme | 96 rxn | EUR 2563.2 |
Universal Solution for DNA isolation (GeDI) |
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E3760-01 | EURx | 25ml | EUR 30.52 |
Universal Solution for DNA isolation (GeDI) |
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E3760-02 | EURx | 100ml | EUR 95.92 |
VAHTS Universal DNA library Prep Kit for MGI V4 |
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NDM610-01 | Vazyme | 24 rxns | EUR 235.2 |
VAHTS Universal DNA library Prep Kit for MGI V4 |
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NDM610-02 | Vazyme | 96 rxns | EUR 880 |
VAHTS Universal DNA library Prep Kit for MGI V3 |
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NDM607-00-6rxns | Vazyme | 6 rxns | EUR 1.09 |
VAHTS Universal DNA library Prep Kit for MGI V3 |
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NDM607-01-24rxns | Vazyme | 24 rxns | EUR 304.66 |
VAHTS Universal DNA library Prep Kit for MGI V3 |
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NDM607-02-96rxns | Vazyme | 96 rxns | EUR 1139.05 |
GeneMATRIX UNIVERSAL DNA/RNA/Protein Purification Kit |
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E3597-01 | EURx | 25preps | EUR 81.75 |
Description: Kit for isolation of total DNA/RNA/Protein from the same biological sample(bacteria, tissue, plant, yeast, cell culture) |
GeneMATRIX UNIVERSAL DNA/RNA/Protein Purification Kit |
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E3597-02 | EURx | 100preps | EUR 299.75 |
Description: Kit for isolation of total DNA/RNA/Protein from the same biological sample(bacteria, tissue, plant, yeast, cell culture) |
Methylamp Universal Methylated DNA Preparation Kit |
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P-1019 | EpiGentek | 40 µg | EUR 416.7 |
VAHTS Universal DNA Library Prep Kit for Illumina V3 |
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ND607-01 | Vazyme | 24 rxn | EUR 529.2 |
VAHTS Universal DNA Library Prep Kit for Illumina V3 |
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ND607-02 | Vazyme | 96 rxn | EUR 1686 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-01 | Vazyme | 24 rxns | EUR 294 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-02 | Vazyme | 96 rxns | EUR 1100 |
VAHTS Universal DNA Library Prep Kit for Ion Torrent |
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ND701-01 | Vazyme | 24 rxn | EUR 879.6 |
VAHTS Universal DNA Library Prep Kit for Ion Torrent |
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ND701-02 | Vazyme | 96 rxn | EUR 2563.2 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-00-6rxns | Vazyme | 6 rxns | EUR 1.09 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-01-24rxns | Vazyme | 24 rxns | EUR 304.44 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-02-96rxns | Vazyme | 96 rxns | EUR 1139.05 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-03-24rxns | Vazyme | 24 rxns | EUR 269.23 |
VAHTS Universal DNA Library Prep Kit for Illumina V4 |
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ND610-04-96rxns | Vazyme | 96 rxns | EUR 999.53 |
AFTSpin Universal Plant Fast DNA Extraction Kit |
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RK30111 | Abclonal | 50RXN | EUR 69 |
EpiMag High Throughput DNA Isolation Universal Kit |
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P-1022-96 | EpiGentek | 96 Samples | EUR 227.7 |
EpiMag High Throughput DNA Isolation Universal Kit |
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P-1022 | EpiGentek | 96 Samples | EUR 215 |
Universal-1 |
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OD308-1PK | EWC Diagnostics | 1 unit | EUR 2.65 |
Description: Universal-1 |
Universal-1 |
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OD308R-1PK | EWC Diagnostics | 1 unit | EUR 2.65 |
Description: Universal-1 |
VAHTS Universal DNA Library Prep Kit for Ion Torrent V2 |
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ND702-01 | Vazyme | 24 rxns | EUR 294 |
VAHTS Universal DNA Library Prep Kit for Ion Torrent V2 |
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ND702-02 | Vazyme | 96 rxns | EUR 1100 |
Universal Kit for DNA isolation with GeDI Solution |
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E3765-01 | EURx | 25preps | EUR 59.95 |
Universal Kit for DNA isolation with GeDI Solution |
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E3765-02 | EURx | 100preps | EUR 210.37 |
VAHTS Universal Pro DNA Library Prep Kit for MGI |
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NDM608-01 | Vazyme | 24 rxn | EUR 907.2 |
VAHTS Universal Pro DNA Library Prep Kit for MGI |
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NDM608-02 | Vazyme | 96 rxn | EUR 2740.8 |
VAHTS Universal Plus DNA Library Prep Kit for MGI |
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NDM617-01 | Vazyme | 24 rxn | EUR 988.8 |
VAHTS Universal Plus DNA Library Prep Kit for MGI |
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NDM617-02 | Vazyme | 96 rxn | EUR 2889.6 |
VAHTS Universal Pro DNA Library Prep Kit for Illumina |
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ND608-01 | Vazyme | 24 rxn | EUR 558 |
VAHTS Universal Pro DNA Library Prep Kit for Illumina |
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ND608-02 | Vazyme | 96 rxn | EUR 1858.8 |
VAHTS Universal Plus DNA Library Prep Kit for MGI V2 |
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NDM627-01 | Vazyme | 24 rxns | EUR 312.5 |
VAHTS Universal Plus DNA Library Prep Kit for MGI V2 |
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NDM627-02 | Vazyme | 96 rxns | EUR 1150 |
VAHTS Universal Plus DNA Library Prep Kit for MGI V2 |
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NDM627-00-6rxns | Vazyme | 6 rxns | EUR 1.09 |
VAHTS Universal Plus DNA Library Prep Kit for MGI V2 |
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NDM627-01-24rxns | Vazyme | 24 rxns | EUR 323.59 |
VAHTS Universal Plus DNA Library Prep Kit for MGI V2 |
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NDM627-02-96rxns | Vazyme | 96 rxns | EUR 1190.83 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina |
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ND617-01 | Vazyme | 24 rxn | EUR 590.4 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina |
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ND617-02 | Vazyme | 96 rxn | EUR 1926 |
Universal Holder |
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LBI10201 | Westburg | each | EUR 161.87 |
Hexa Universal-2 |
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HX038-1PK | EWC Diagnostics | 1 unit | EUR 2.51 |
Description: Hexa Universal-2 |
VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free) |
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ND607-03 | Vazyme | 24 rxn | EUR 514.8 |
VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free) |
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ND607-04 | Vazyme | 96 rxn | EUR 1624.8 |
Universal Platform |
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SS-300-U | Avans Biotechnology Corp | each | EUR 250 |
Universal Indicator |
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I013-100ML | EWC Diagnostics | 1 unit | EUR 2.65 |
Description: Universal Indicator |
Universal Indicator |
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I013-500ML | EWC Diagnostics | 1 unit | EUR 9.01 |
Description: Universal Indicator |
VAHTS Universal Plus DNA Library Prep Kit for Illumina V2 |
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ND627-01 | Vazyme | 24 rxns | EUR 312.5 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina V2 |
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ND627-02 | Vazyme | 96 rxns | EUR 1150 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina V2 |
|||
ND627-00-6rxns | Vazyme | 6 rxns | EUR 1.09 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina V2 |
|||
ND627-01-24rxns | Vazyme | 24 rxns | EUR 323.59 |
VAHTS Universal Plus DNA Library Prep Kit for Illumina V2 |
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ND627-02-96rxns | Vazyme | 96 rxns | EUR 1190.83 |
Hexa Universal - 1 |
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HX032-1PK | EWC Diagnostics | 1 unit | EUR 2.51 |
Description: Hexa Universal - 1 |
Hexa Universal - 4 |
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HX715-1PK | EWC Diagnostics | 1 unit | EUR 2.51 |
Description: Hexa Universal - 4 |
Hexa Universal - 5 |
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HX716-1PK | EWC Diagnostics | 1 unit | EUR 2.51 |
Description: Hexa Universal - 5 |
Icosa Universal - 1 |
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IC001-1PK | EWC Diagnostics | 1 unit | EUR 9.32 |
Description: Icosa Universal - 1 |
Icosa Universal - 2 |
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IC006-1PK | EWC Diagnostics | 1 unit | EUR 9.32 |
Description: Icosa Universal - 2 |
Dodeca Universal -XI |
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DE026-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal -XI |
Dodeca - Universal XV, |
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DE042-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca - Universal XV, |
Universal V1-Puck |
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M-CP-111-021 | MiTeGen | 1 PUCK | EUR 350 |
Description: Universal V1-Puck |
UNIVERSAL BEER AGAR |
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U21-100-10kg | Alphabiosciences | 10 kg | EUR 1828.8 |
UNIVERSAL BEER AGAR |
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U21-100-2kg | Alphabiosciences | 2kg | EUR 444 |
UNIVERSAL BEER AGAR |
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U21-100-500g | Alphabiosciences | 500 g | EUR 164.4 |
Dodeca Universal-I |
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DE001-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-I |
Dodeca Universal-V |
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DE013-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-V |
Dodeca Universal -XII |
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DE027-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal -XII |
Dodeca Universal XIV |
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DE035-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal XIV |
Universal WB Toolkit |
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KTD106-EN-each | Abbkine | each | Ask for price |
Universal WB Toolkit |
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KTD106-EN-Null | Abbkine | Null | Ask for price |
Universal WB Toolkit |
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KTD106-EN-20T | Abbkine | 20 T | EUR 59 |
Description: Abbkine has developed a Universal WB Toolkit. After careful design and research, one-stop operation can meet the needs of routine WB experiments and obtain excellent experimental results. |
Universal WB Toolkit |
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MBS9719335-20Tests | MyBiosource | 20Tests | EUR 195 |
Universal WB Toolkit |
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MBS9719335-5x20Tests | MyBiosource | 5x20Tests | EUR 885 |
Dodeca Universal-II |
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DE007-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-II |
Dodeca Universal-IV |
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DE012-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-IV |
Dodeca Universal-VI |
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DE014-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-VI |
Dodeca Universal-IX |
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DE017-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-IX |
Dodeca Universal- XIII |
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DE028-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal- XIII |
Dodeca Universal-III |
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DE008-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-III |
Dodeca Universal-VII |
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DE015-1PK | EWC Diagnostics | 1 unit | EUR 3.96 |
Description: Dodeca Universal-VII |
APP Antibody (universal) |
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GWB-C298C6 | GenWay Biotech | 0.1 ml | Ask for price |
Universal qPCR Mixture |
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QPCR1000-UNIV | Bio Basic | 4X1.25ml | EUR 331.44 |
NBS Universal Platform |
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SHA4070 | Scientific Laboratory Supplies | EACH | EUR 708.93 |
NBS Universal Platform |
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SHA4232 | Scientific Laboratory Supplies | EACH | EUR 388.8 |
NBS Universal Platform |
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SHA4256 | Scientific Laboratory Supplies | EACH | EUR 476.61 |
NBS Universal Platform |
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SHA4272 | Scientific Laboratory Supplies | EACH | EUR 756.04 |
NBS Universal Platform |
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SHA4290 | Scientific Laboratory Supplies | EACH | EUR 1016.3 |
Universal Block Buffer |
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TBS5013 | Tribioscience | 100 ml | EUR 60 |
Universal Basal Medium |
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cAP-01C | Angio Proteomie | 500ml | EUR 64.35 |
*Universal Liquid Medium |
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M1332-500G | EWC Diagnostics | 1 unit | EUR 25.78 |
Description: *Universal Liquid Medium |
Universal vessel holder |
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LBI10230 | Westburg | each | EUR 156.96 |
Universal platform - EACH |
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INC1112 | Scientific Laboratory Supplies | EACH | EUR 1613.25 |
Universal Growth Medium |
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cAP-01B | Angio Proteomie | 500ml | EUR 89.1 |
Universal Heating System |
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LBI10501 | Westburg | each | EUR 11281.5 |
Universal Spring Platform |
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H1000-P-SP | Benchmark Scientific | 1 PC | EUR 660.13 |
Universal Spring Platform |
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H1010-P-SP | Benchmark Scientific | 1 each | EUR 697.83 |
Universal Attachment - EACH |
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MIX1320 | Scientific Laboratory Supplies | EACH | EUR 322.65 |
Universal Coating Solution |
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MBS556488-20mL | MyBiosource | 20mL | EUR 310 |
Universal Coating Solution |
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MBS556488-5x20mL | MyBiosource | 5x20mL | EUR 1235 |
Universal Oven UN30 - EACH |
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OVE8314 | Scientific Laboratory Supplies | EACH | EUR 1881.9 |
Universal Oven UN55 - EACH |
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OVE8316 | Scientific Laboratory Supplies | EACH | EUR 2196.45 |
Universal Oven UN75 - EACH |
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OVE8318 | Scientific Laboratory Supplies | EACH | EUR 2281.5 |
Universal Oven UF30 - EACH |
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OVE8332 | Scientific Laboratory Supplies | EACH | EUR 2150.55 |
Universal Oven UF55 - EACH |
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OVE8334 | Scientific Laboratory Supplies | EACH | EUR 2594.7 |
Universal Oven UF75 - EACH |
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OVE8336 | Scientific Laboratory Supplies | EACH | EUR 2737.8 |
Universal Restriction Buffer |
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EN-300 | Jena Bioscience GmbH | 5 x 1ml | EUR 22.7 |
Grant Universal Tray - EACH |
|||
BAT4622 | Scientific Laboratory Supplies | EACH | EUR 353.7 |
Universal AC adapter - EACH |
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PIP3214 | Scientific Laboratory Supplies | EACH | EUR 87.75 |
Universal Oven UN110 - EACH |
|||
OVE8320 | Scientific Laboratory Supplies | EACH | EUR 2922.75 |
Universal Oven UN160 - EACH |
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OVE8322 | Scientific Laboratory Supplies | EACH | EUR 3524.85 |
Universal Oven UN260 - EACH |
|||
OVE8324 | Scientific Laboratory Supplies | EACH | EUR 4666.95 |
Universal Oven UN450 - EACH |
|||
OVE8326 | Scientific Laboratory Supplies | EACH | EUR 6176.25 |
Universal Oven UN750 - EACH |
|||
OVE8328 | Scientific Laboratory Supplies | EACH | EUR 8275.5 |
Universal Oven UF110 - EACH |
|||
OVE8338 | Scientific Laboratory Supplies | EACH | EUR 3235.95 |
Universal Oven UF160 - EACH |
|||
OVE8340 | Scientific Laboratory Supplies | EACH | EUR 4207.95 |
Universal Oven UF260 - EACH |
|||
OVE8342 | Scientific Laboratory Supplies | EACH | EUR 5364.9 |
Universal Oven UF450 - EACH |
|||
OVE8344 | Scientific Laboratory Supplies | EACH | EUR 7025.4 |
Universal Oven UF750 - EACH |
|||
OVE8346 | Scientific Laboratory Supplies | EACH | EUR 9309.6 |
Universal Detachment Solution |
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AD002 | Neuromics | 100 ml | EUR 177.6 |
UNIVERSAL PREENRICHMENT BROTH |
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U21-101-10kg | Alphabiosciences | 10 kg | EUR 898.8 |
UNIVERSAL PREENRICHMENT BROTH |
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U21-101-2Kg | Alphabiosciences | 2 Kg | EUR 242.4 |
UNIVERSAL PREENRICHMENT BROTH |
|||
U21-101-500g | Alphabiosciences | 500 g | EUR 109.2 |
Universal Detachment Solution |
|||
MBS556489-100mL | MyBiosource | 100mL | EUR 185 |
Universal Detachment Solution |
|||
MBS556489-5x100mL | MyBiosource | 5x100mL | EUR 680 |
Ilford Universal Stop Bath |
|||
21956-500 | Polysciences Europe GmbH | 500ml | EUR 73 |
Universal Spring Tray - EACH |
|||
BAT7177 | Scientific Laboratory Supplies | EACH | EUR 336.15 |
PCR plate-foil universal |
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A28216 | GeneOn | 1x100 pcs | EUR 112.8 |
PCR plate-foil universal |
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A28216L | GeneOn | 5x100 pcs | EUR 372 |
Universal Oven UF1060 - EACH |
|||
OVE8348 | Scientific Laboratory Supplies | EACH | EUR 17192.25 |
MGI Universal Blockers-S |
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RK20278 | Abclonal | 4RXN | EUR 425.1 |
MGI Universal Blockers-D |
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RK20279 | Abclonal | 4RXN | EUR 425.1 |
5min Universal Ligation Mix |
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C311-01 | Vazyme | 50 rxn | EUR 72.5 |
5min Universal Ligation Mix |
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C311-02 | Vazyme | 100 rxn | EUR 116 |
18mm Mag Universal ScrewCap |
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CHR3468 | Scientific Laboratory Supplies | PK1000 | EUR 791.85 |
The ensuing vector can displace goal plasmids from a laboratory inhabitants with out choice and demonstrated exercise in a mouse mannequin though unfold is much less environment friendly and requires further choice stress.